Clobetasol propionate comes as a foam, spray, cream, gel, ointment, or shampoo. If applying a spray, gel, cream, or ointment to the skin, wash and dry the affected area and your hands before apply the medication. Cover the area with a thin layer of medication and rub it in gently. Allow the medication to dry before covering it with clothing. Do not wrap or bandage the area unless specified by your doctor. If using the clobetasol propionate shampoo to treat the scalp, part your hair to expose the affected area. Apply the shampoo to the affected area only on your dry scalp and massage it in gently. Let the shampoo sit for 15 minutes. Then add water, lather the shampoo in the area and rinse it out well. Because clobetasol propionate is a powerful corticosteroid, it should not be used for more than two weeks and should not be used on face, groin, or arm pit areas. Do not cover the affected area with makeup or cosmetics.