Beleodaq (belinostat) for injection is supplied as a sterile lyophilized yellow powder containing 500 mg belinostat as the active ingredient. Each vial also contains 1000 mg L-Arginine, USP as an inactive ingredient. The drug product is supplied in a single-dose 30 mL clear glass vial with a coated stopper and aluminum crimp seal with “flip-off” cap. Beleodaq is intended for intravenous administration after reconstitution with 9 mL Sterile Water for injection, and the reconstituted solution is further diluted with 250 mL of sterile % Sodium Chloride injection prior to infusion [see Dosage and Administration ( 2) ] .
Not surprisingly, no elevated risk was found in the three studies listed at bottom, which looked at urine metabolite levels rather than blood THC. This confirms that urine testing has no bearing on driving impairment. Despite this fact, US Department of Transportation regulations force millions of commercial drivers to submit to random urine testing. The government has never produced convincing scientific evidence that this policy is necessary or effective to protect public safety. But they're the government, so they don't have to provide any evidence!
The optimal dosage levels of CBD are uncertain due to a lack of human studies. Chronic high doses of up to 1500 mg per day are well tolerated and produce no noticeable physiological effects. However, there is evidence to suggest that the medical benefits of CBD disappear when dosages become excessive. For inhaled medical use, most users prefer varieties with THC:CBD ratios between 2:1 and 1:2. Extremely low-THC varieties are useful for making CBD extracts and tinctures. Unlike THC, CBD does not show up positive on standard drug tests for marijuana.