All bets are off the table when high-dose testosterone and its many metabolites are used illegally, such as with anabolic steroid abuse. Strokes, embolisms, and cardiovascular disease are all more likely, as is sudden death, and liver and kidney disease. 44 In women, acne, irreversible deepening of the voice, baldness, increased facial hair, enlarged sex organs, breast reduction, depression, and infertility have all been reported. In adult men that abuse anabolic steroids, acne, baldness, permanent infertility, gynecomastia, loss of libido, erectile dysfunction, testicle shrinkage, and profuse sweating are all reported side effects. Increased testicular cancer hasn't been reported, though. 45,46
A European Union scientific commission was asked to report on the incidence of mastitis and other disorders in dairy cows and on other aspects of the welfare of dairy cows. The commission's statement, subsequently adopted by the European Union, stated that the use of rBST substantially increased health problems with cows , including foot problems , mastitis and injection site reactions, impinged on the welfare of the animals and caused reproductive disorders . The report concluded that, on the basis of the health and welfare of the animals, rBST should NOT be used . Health Canada prohibited the sale of rBST in 1999 ; the external committees found that, although there was no significant health risk to humans, the drug presents a threat to animal health, and, for this reason, cannot be sold in Canada .